Year : 2021 | Volume
: 4 | Issue : 1 | Page : 28--33
Impact of sleep quality on cognitive functions in Parkinson’s disease
Saurav Aggrawal, Birinder Singh Paul, Gagandeep Singh, Rajinder Kumar Bansal
Oswal Hospital, Ludhiana, Punjab, India
BACKGROUND: Sleep disorders lead to cognitive deficits in healthy people and are thought to have significant impact on cognition in Parkinson’s disease (PD). OBJECTIVE: To study the sleep pattern and its relationship to cognitive functioning in non-demented PD cohort. MATERIALS AND METHODS: Sleep was evaluated by Pittsburg Sleep Quality Index (PSQI) in a cohort of PD patients. Comprehensive assessment of cognitive domains including attention, executive functions, short/long-term verbal memory, visual memory, and visuospatial functioning was done by battery of neuro-physiological tests on patients in “ON” state. Based on the component PSQI sleep score, patients were grouped as having «DQ»good quality sleep«DQ» (PSQI score ≤ 5) or «DQ»poor quality sleep«DQ» (PSQI score > 5). The demographic profile, disease characteristics, treatment, and cognitive tests were then compared between the two groups. RESULTS: Of 130 patients with diagnosis of PD, 85 patients were included. 63 (74.1%) had good sleep quality while 22 (25.9%) had poor sleep quality. Mean age and disease characteristic were comparable between two groups except that females had statistically significant (P = 0.001) poor sleep quality as compared to men. Poor sleep quality had significant effect on cognitive functions including generativity, inhibition, set-shifting, perseveration, and attention but there was no impact of sleep on verbal memory, visual memory, and visuospatial abilities. CONCLUSION: PD patients with poor sleep quality on PSQI questionnaire should be carefully screened for presence of any cognitive impairment especially executive impairment, as these two may be inter-related. Intervention to improve sleep would have far reaching benefits to improve the quality of life of PD patients.
Prof. Birinder Singh Paul
Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, Punjab.
|How to cite this article:|
Aggrawal S, Paul BS, Singh G, Bansal RK. Impact of sleep quality on cognitive functions in Parkinson’s disease.Ann Mov Disord 2021;4:28-33
|How to cite this URL:|
Aggrawal S, Paul BS, Singh G, Bansal RK. Impact of sleep quality on cognitive functions in Parkinson’s disease. Ann Mov Disord [serial online] 2021 [cited 2022 Dec 1 ];4:28-33
Available from: https://www.aomd.in/article.asp?issn=2590-3446;year=2021;volume=4;issue=1;spage=28;epage=33;aulast=Aggrawal;type=0