Annals of Movement Disorders

ORIGINAL ARTICLES
Year
: 2021  |  Volume : 4  |  Issue : 1  |  Page : 28--33

Impact of sleep quality on cognitive functions in Parkinson’s disease


Saurav Aggrawal, Birinder Singh Paul, Gagandeep Singh, Rajinder Kumar Bansal 
 Oswal Hospital, Ludhiana, Punjab, India

Correspondence Address:
Prof. Birinder Singh Paul
Department of Neurology, Dayanand Medical College and Hospital, Ludhiana, Punjab.
India

BACKGROUND: Sleep disorders lead to cognitive deficits in healthy people and are thought to have significant impact on cognition in Parkinson’s disease (PD). OBJECTIVE: To study the sleep pattern and its relationship to cognitive functioning in non-demented PD cohort. MATERIALS AND METHODS: Sleep was evaluated by Pittsburg Sleep Quality Index (PSQI) in a cohort of PD patients. Comprehensive assessment of cognitive domains including attention, executive functions, short/long-term verbal memory, visual memory, and visuospatial functioning was done by battery of neuro-physiological tests on patients in “ON” state. Based on the component PSQI sleep score, patients were grouped as having DQgood quality sleepDQ (PSQI score ≤ 5) or DQpoor quality sleepDQ (PSQI score > 5). The demographic profile, disease characteristics, treatment, and cognitive tests were then compared between the two groups. RESULTS: Of 130 patients with diagnosis of PD, 85 patients were included. 63 (74.1%) had good sleep quality while 22 (25.9%) had poor sleep quality. Mean age and disease characteristic were comparable between two groups except that females had statistically significant (P = 0.001) poor sleep quality as compared to men. Poor sleep quality had significant effect on cognitive functions including generativity, inhibition, set-shifting, perseveration, and attention but there was no impact of sleep on verbal memory, visual memory, and visuospatial abilities. CONCLUSION: PD patients with poor sleep quality on PSQI questionnaire should be carefully screened for presence of any cognitive impairment especially executive impairment, as these two may be inter-related. Intervention to improve sleep would have far reaching benefits to improve the quality of life of PD patients.


How to cite this article:
Aggrawal S, Paul BS, Singh G, Bansal RK. Impact of sleep quality on cognitive functions in Parkinson’s disease.Ann Mov Disord 2021;4:28-33


How to cite this URL:
Aggrawal S, Paul BS, Singh G, Bansal RK. Impact of sleep quality on cognitive functions in Parkinson’s disease. Ann Mov Disord [serial online] 2021 [cited 2022 Dec 1 ];4:28-33
Available from: https://www.aomd.in/article.asp?issn=2590-3446;year=2021;volume=4;issue=1;spage=28;epage=33;aulast=Aggrawal;type=0