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  Indian J Med Microbiol
 

Figure 1: Pedigree structure of dentatorubral–pallidoluysian atrophy (DRPLA) CAG expansion positive kindred showing multiple affected individuals and phenomena of anticipation observed (upper panel). Magnetic resonance imaging (MRI) brains, T2, and fluid-attenuated inversion recovery (FLAIR) axial images showing multiple punctuate hyperintensities in centrum semiovale and paraventricular white matter and atrophy of cerebellum and brain stem (lower left panel). Fragment analysis results showing profile of expanded repeats in affected individuals (lower right panel)

Figure 1: Pedigree structure of dentatorubral–pallidoluysian atrophy (DRPLA) CAG expansion positive kindred showing multiple affected individuals and phenomena of anticipation observed (upper panel). Magnetic resonance imaging (MRI) brains, T2, and fluid-attenuated inversion recovery (FLAIR) axial images showing multiple punctuate hyperintensities in centrum semiovale and paraventricular white matter and atrophy of cerebellum and brain stem (lower left panel). Fragment analysis results showing profile of expanded repeats in affected individuals (lower right panel)